BDBM488044 4-(1-Ethyl-3-(pyridin- 3-yl)-1H-pyrazol-4- yl)-N-(4-(2-(4-(2- methoxyethyl)piperazin-1- yl)ethyl)phenyl)pyrimidin- 2-amine::US10954216, Example 43

SMILES CCn1cc(c(n1)-c1cccnc1)-c1ccnc(Nc2ccc(CCN3CCN(CCOC)CC3)cc2)n1

InChI Key InChIKey=GADJBNYUDWRSOH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488044   

TargetActivin receptor type-1 [R206H](Homo sapiens (Human))
Riken

US Patent
LigandPNGBDBM488044(4-(1-Ethyl-3-(pyridin- 3-yl)-1H-pyrazol-4- yl)-N-(...)
Affinity DataIC50:  24.9nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent