BDBM488047 4-(1-Ethyl-3-(pyridin- 3-yl)-1H-pyrazol-4- yl)-N-(4-(4- methylpiperazin-1- yl)phenyl)pyrimidin-2- amine::US10954216, Example 46
SMILES CCn1cc(c(n1)-c1cccnc1)-c1ccnc(Nc2ccc(cc2)N2CCN(C)CC2)n1
InChI Key InChIKey=SPIIJYVAXDYAEG-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 488047
Affinity DataIC50: 25.5nMAssay Description:TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair