BDBM488054 2-Methyl-1-(4-(2-((2- methyl-1,2,3,4- tetrahydroisoquinolin- 6-yl)amino)pyrimidin- 4-yl)-3-(pyridin-3-yl)- 1H-pyrazol-1- yl)propan-2-ol::US10954216, Example 65

SMILES CN1CCc2cc(Nc3nccc(n3)-c3cn(CC(C)(C)O)nc3-c3cccnc3)ccc2C1

InChI Key InChIKey=SAYPSSQDJVYOAF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488054   

TargetActivin receptor type-1 [R206H](Homo sapiens (Human))
Riken

US Patent
LigandPNGBDBM488054(2-Methyl-1-(4-(2-((2- methyl-1,2,3,4- tetrahydrois...)
Affinity DataIC50:  6.70nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent