BDBM488074 1-(4-(4-((4-(1-ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- yl)pyrimidin-2- yl)amino)phenyl) piperazin-1-yl)-2- methylpropan-2-ol::US10954216, Example 104
SMILES CCn1cc(c(n1)-c1cccnc1)-c1ccnc(Nc2ccc(cc2)N2CCN(CC(C)(C)O)CC2)n1
InChI Key InChIKey=PRWYUWMVUBDGSQ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 488074
Affinity DataIC50: 13.2nMAssay Description:TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair