BDBM488075 1-(4-(4-((4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- yl)pyrimidin-2- yl)amino)phenyl) piperazin-1-yl)-3- methoxypropan-2-ol::US10954216, Example 105

SMILES CCn1cc(c(n1)-c1cccnc1)-c1ccnc(Nc2ccc(cc2)N2CCN(CC(O)COC)CC2)n1

InChI Key InChIKey=NFIQPRHATXPTAP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488075   

TargetActivin receptor type-1 [R206H](Homo sapiens (Human))
Riken

US Patent
LigandPNGBDBM488075(1-(4-(4-((4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol...)
Affinity DataIC50:  9.90nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent