BDBM488079 (4-((4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- yl)pyrimidin-2- yl)amino)phenyl) (8-methyl-3,8- diazabicyclo [3.2.1] octan-3- yl)methanone::US10954216, Example 117

SMILES CCn1cc(c(n1)-c1cccnc1)-c1ccnc(Nc2ccc(cc2)C(=O)N2CC3CCC(C2)N3C)n1

InChI Key InChIKey=XDMIWNRCLWCODO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 488079   

TargetActivin receptor type-1(Homo sapiens (Human))
Riken

US Patent
LigandPNGBDBM488079((4-((4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- y...)
Affinity DataIC50:  7.90nMAssay Description:TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivin receptor type-1 [R206H](Homo sapiens (Human))
Riken

US Patent
LigandPNGBDBM488079((4-((4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- y...)
Affinity DataIC50:  6.30nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent