BDBM488089 4-(1-(2,2- Difluoroethyl)-3- (pyridin-3-yl)-1H- pyrazol-4-yl)-N-(4- (piperazin-1- yl)phenyl)pyrimidin-2- amine::US10954216, Example 149
SMILES FC(F)Cn1cc(c(n1)-c1cccnc1)-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1
InChI Key InChIKey=UEEBJGBKQPWCST-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 488089
Affinity DataIC50: 62.5nMAssay Description:TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair