BDBM488104 N-(4-(4-Amino-4- ethylpiperidin-1- yl)phenyl)-4-(1-ethyl- 3-(pyridin-3-yl)-1H- pyrazol-4- yl)pyrimidin-2-amine::US10954216, Example 177
SMILES CCn1cc(c(n1)-c1cccnc1)-c1ccnc(Nc2ccc(cc2)N2CCC(N)(CC)CC2)n1
InChI Key InChIKey=HBALAPRVSOJBQZ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 488104
Affinity DataIC50: 3.5nMAssay Description:TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair