BDBM488190 2-(5-(cyclopropylmethyl)-3- (3-(pyrrolidine-1- carbonyl)phenyl)-4-(4- sulfamoylbenzyl)-1H-pyrazol- 1-yl)thiazole-4-carboxylic acid::US10954228, Compound 145

SMILES OC(=O)c1csc(n1)-n1nc(c(Cc2ccc(cc2)[SH+]([O-])=O)c1CC1CC1)-c1cccc(c1)C(=O)N1CCCC1

InChI Key InChIKey=AZUZTEPVZQCFLY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488190   

TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
The Trustees of The University of Pennsylvania

US Patent
LigandPNGBDBM488190(2-(5-(cyclopropylmethyl)-3- (3-(pyrrolidine-1- car...)
Affinity DataIC50: <100nMAssay Description:Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent