BDBM488192 2-(3-(3-(tert-butylcarbamoyl)-4- fluorophenyl)-5- (cyclopropylmethyl)- 4-(3-fluoro-4-sulfamoylbenzyl)- 1H-pyrazol-1-yl) thiazole-4-carboxylic acid::US10954228, Compound 147

SMILES CC(C)(C)NC(=O)c1cc(ccc1F)-c1nn(c(CC2CC2)c1Cc1ccc(c(F)c1)[S+](N)([O-])=O)-c1nc(cs1)C(O)=O

InChI Key InChIKey=LBQXWFKYDZBXOR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488192   

TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
The Trustees of The University of Pennsylvania

US Patent
LigandPNGBDBM488192(2-(3-(3-(tert-butylcarbamoyl)-4- fluorophenyl)-5- ...)
Affinity DataIC50: <100nMAssay Description:Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent