BDBM489325 3-(benzo[d]thiazol-2-yl)-5-(4-(methylsulfonyl)phenyl)pyrazin-2-amine ::BDBM50341757::US10961232, Compound I-146
SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc(N)c(n1)C1=[S]c2ccccc2N1
InChI Key InChIKey=LBFRVTYJRMMGTH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 489325
Affinity DataKi: 55nMAssay Description:Compounds were screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays were carried out in a mixtu...More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 55nMAssay Description:Compounds were screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays were carried out in a mixtu...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 22nMAssay Description:Inhibition of full length recombinant ATR after 24 hrs by radiometric phosphate incorporation assayMore data for this Ligand-Target Pair
Ligand Info
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of DNAPK after 2 hrs by radiometric phosphate incorporation assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 720nMAssay Description:Inhibition of full length recombinant ATM after 24 hrs by radiometric phosphate incorporation assayMore data for this Ligand-Target Pair
Ligand Info