BDBM489400 US10961247, Ex. No. 15

SMILES FC(F)Cn1cc(Nc2nc(N[C@@H]3CCCN(C3)C(=O)C=C)c3cc[nH]c3n2)cn1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 489400   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM489400(US10961247, Ex. No. 15)
Affinity DataIC50:  7.20nMAssay Description:JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM489400(US10961247, Ex. No. 15)
Affinity DataIC50:  0.300nMAssay Description:JAK3 and BTK kinase inhibitory activities were measured for the compounds prepared in the above Examples through in vitro analysis on the ADP Glow (G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent