BDBM490340 5-fluoro-N-(4-fluoro-2-methylphenyl)-4-(3-oxo-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-2-[(2S)-pentan-2-yloxy]benzamide::US10968216, Example 8
SMILES CCC[C@H](C)Oc1cc(c(F)cc1C(=O)Nc1ccc(F)cc1C)-n1nc2CCCCn2c1=O
InChI Key InChIKey=XXECZSNEAKDCDU-INIZCTEOSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 490340
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
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US Patent
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US Patent
Affinity DataIC50: 4.5nMAssay Description:Assay—1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair