BDBM490401 5-fluoro-N-(2-methoxy-6-methylphenyl)-4-(3-oxo-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-2-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}benzamide::US10968216, Example 69
SMILES COc1cccc(C)c1NC(=O)c1cc(F)c(cc1O[C@@H](C)C(F)(F)F)-n1nc2CCCCn2c1=O
InChI Key InChIKey=PYHVWRZIPHSCRW-AWEZNQCLSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 490401
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
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Affinity DataIC50: 6nMAssay Description:Assay—1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair