BDBM490420 5-fluoro-N-[2-methyl-6-(trifluoromethyl)phenyl]-4-(3-oxo-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)-2-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}benzamide::US10968216, Example 88
SMILES C[C@H](Oc1cc(c(F)cc1C(=O)Nc1c(C)cccc1C(F)(F)F)-n1nc2CCCCn2c1=O)C(F)(F)F
InChI Key InChIKey=MPPAZDICWXHVOB-ZDUSSCGKSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 490420
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
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Affinity DataIC50: <5nMAssay Description:Assay—1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair