BDBM490450 2-[(1S)-1-cyclohexylethoxy]-5-fluoro-N-(2-methoxy-4-methylpyridin-3-yl)-4-(3-oxo-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)benzamide::US10968216, Example 118

SMILES COc1nccc(C)c1NC(=O)c1cc(F)c(cc1O[C@@H](C)C1CCCCC1)-n1nc2CCCCn2c1=O

InChI Key InChIKey=SYQXUVNANHQKQZ-SFHVURJKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 490450   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
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US Patent
LigandPNGBDBM490450(2-[(1S)-1-cyclohexylethoxy]-5-fluoro-N-(2-methoxy-...)
Affinity DataIC50:  2.5nMAssay Description:Assay—1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent