BDBM490564 N-(2-chloro-4-fluoro-6-methylphenyl)-5-fluoro-4-(3-oxo-6,7-dihydro-3H,5H-[1,2,4]triazolo[3,4-c][1,4]oxazepin-2(9H)-yl)-2-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}benzamide::US10968216, Example 232

SMILES C[C@H](Oc1cc(c(F)cc1C(=O)Nc1c(C)cc(F)cc1Cl)-n1nc2COCCCn2c1=O)C(F)(F)F

InChI Key InChIKey=WEDFPOYPQONFHE-LBPRGKRZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 490564   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
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US Patent
LigandPNGBDBM490564(N-(2-chloro-4-fluoro-6-methylphenyl)-5-fluoro-4-(3...)
Affinity DataIC50:  2.90nMAssay Description:Assay—1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent