BDBM490568 N-(2,6-dichloro-4-fluorophenyl)-5-fluoro-4-(3-oxo-6,7-dihydro-3H,5H-[1,2,4]triazolo[3,4-c]-[1,4]oxazepin-2(9H)-yl)-2-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}benzamide::US10968216, Example 236
SMILES C[C@H](Oc1cc(c(F)cc1C(=O)Nc1c(Cl)cc(F)cc1Cl)-n1nc2COCCCn2c1=O)C(F)(F)F
InChI Key InChIKey=QNDAASQAXIFVQU-JTQLQIEISA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 490568
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
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US Patent
Affinity DataIC50: 4.10nMAssay Description:Assay—1: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair