BDBM490802 4-Chloro-1-ethyl-5-(2-methoxy-4-((R*)-3,3,3-trifluoro-2-methylpropyl)phenyl)-N-(((1r,4R)-4-(methylsulfonyl)cyclohexyl)methyl)-1H-pyrazole-3-carboxamide::Step b::US10975037, Example 1

SMILES CCn1nc(C(=O)NC[C@H]2CC[C@@H](CC2)S(C)(=O)=O)c(Cl)c1-c1ccc(C[C@@H](C)C(F)(F)F)cc1OC

InChI Key InChIKey=NSKKKYFGRDTYQB-JFIYKMOQSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 490802   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490802(4-Chloro-1-ethyl-5-(2-methoxy-4-((R*)-3,3,3-triflu...)
Affinity DataKd:  0.600nMAssay Description:ThermoFluorŪ experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensiona...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent