BDBM490830 4-Chloro-1-isobutyl-5-(2-methoxy-4-(((R)-1,1,1-trifluoropropan-2-yl)amino)phenyl)-N-(((1r,4R)-4-(methylsulfonyl)cyclohexyl)methyl)-1H-pyrazole-3-carboxamide::US10975037, Example 28

SMILES COc1cc(N[C@H](C)C(F)(F)F)ccc1-c1c(Cl)c(nn1CC(C)C)C(=O)NC[C@H]1CC[C@@H](CC1)S(C)(=O)=O

InChI Key InChIKey=OEKIBCVHMSSHLH-ZHALLVOQSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 490830   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490830(4-Chloro-1-isobutyl-5-(2-methoxy-4-(((R)-1,1,1-tri...)
Affinity DataKd:  2.5nMAssay Description:ThermoFluorŪ experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensiona...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent