BDBM490841 4-Chloro-1-ethyl-N-(((1s,4s)-1-hydroxy-4-(methylsulfonyl)cyclohexyl)methyl)-5-(2-methoxy-4-(3,3,3-trifluoropropyl)phenyl)-1H-pyrazole-3-carboxamide::US10975037, Example 39

SMILES CCn1nc(C(=O)NC[C@@]2(O)CC[C@@H](CC2)S(C)(=O)=O)c(Cl)c1-c1ccc(CCC(F)(F)F)cc1OC

InChI Key InChIKey=UPTWUVBJOPALSM-PAVFIEEWSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 490841   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490841(4-Chloro-1-ethyl-N-(((1s,4s)-1-hydroxy-4-(methylsu...)
Affinity DataKd:  10nMAssay Description:ThermoFluorŪ experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensiona...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent