BDBM490945 5-(2-(Difluoromethoxy)-4-((R*)-3,3,3-trifluoro-2-methylpropyl)phenyl)-N-(((1R*,2R*,4R*)-1,2-dihydroxy-4-(methylsulfonyl)cyclohexyl)methyl)-1-ethyl-4-methyl-1H-pyrazole-3-carboxamide::US10975037, Example 140

SMILES CCn1nc(C(=O)NC[C@]2(O)CC[C@H](C[C@H]2O)S(C)(=O)=O)c(C)c1-c1ccc(C[C@@H](C)C(F)(F)F)cc1OC(F)F

InChI Key InChIKey=FAUXDVQQCAAPTO-JSWAKPCCSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 490945   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490945(5-(2-(Difluoromethoxy)-4-((R*)-3,3,3-trifluoro-2-m...)
Affinity DataKd:  2.40nMAssay Description:ThermoFluorŪ experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensiona...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent