BDBM491852 N-(1-cyclopentyl- 2-(1H-indol-3- yl)ethyl)-2-(4- methylpiperazin- 1-yl)thiazole-5- carboxamide::US10975066, Example 15

SMILES CN1CCN(CC1)c1ncc(s1)C(=O)NC(Cc1c[nH]c2ccccc12)C1CCCC1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491852   

TargetAlpha-synuclein(Homo sapiens (Human))
Ucb Biopharma

US Patent
LigandPNGBDBM491852(N-(1-cyclopentyl- 2-(1H-indol-3- yl)ethyl)-2-(4- m...)
Affinity DataIC50:  2.20E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent