BDBM492457 6-(1-methylethyl)-5-[1- (1-methylethyl)-1H-pyrazol-4- yl][1,2,4]triazolo[1,5- a]pyrimidin-7(4H)-one::US10975084, Example 11-20

SMILES CC(C)c1c([nH]c2ncnn2c1=O)-c1cnn(c1)C(C)C

InChI Key InChIKey=AYZPIVPCIKYUDA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492457   

TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492457(6-(1-methylethyl)-5-[1- (1-methylethyl)-1H-pyrazol...)
Affinity DataIC50:  5.08nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent