BDBM492874 N-((5-chloro-1H- indazol-3-yl)methyl)-5- (4- (trifluoromethyl)benzyl) nicotinamide::US10981893, Example 3

SMILES FC(F)(F)c1ccc(Cc2cncc(c2)C(=O)NCc2n[nH]c3ccc(Cl)cc23)cc1

InChI Key InChIKey=VPKUXXXYKMYIMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492874   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM492874(N-((5-chloro-1H- indazol-3-yl)methyl)-5- (4- (trif...)
Affinity DataIC50:  5.50E+3nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent