BDBM492876 5-benzyl-N-((5-chloro- 1H-indazol-3- yl)methyl)nicotinamide::US10981893, Example 5

SMILES Clc1ccc2[nH]nc(CNC(=O)c3cncc(Cc4ccccc4)c3)c2c1

InChI Key InChIKey=SOYJMMULNNSPNJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492876   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM492876(5-benzyl-N-((5-chloro- 1H-indazol-3- yl)methyl)nic...)
Affinity DataIC50:  5.50E+3nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent