BDBM492877 5-(2-carbamoylbenzyl)- N-((5-chloro-1H- indazol-3- yl)methyl)nicotinamide::US10981893, Example 6

SMILES NC(=O)c1ccccc1Cc1cncc(c1)C(=O)NCc1n[nH]c2ccc(Cl)cc12

InChI Key InChIKey=ZITGZLAGIRUYRB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492877   

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandPNGBDBM492877(US10981893, Example 6 | 5-(2-carbamoylbenzyl)- N-(...)
Affinity DataIC50: 5.50E+3nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
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Date in BDB:
10/26/2021
Entry Details
US Patent