BDBM492878 N-((3-chloro-6-fluoro- 1H-indol-5-yl)methyl)- 5-((4-cyano-1H- pyrazol-1- yl)methyl)nicotinamide::US10981893, Example 7

SMILES Fc1cc2[nH]cc(Cl)c2cc1CNC(=O)c1cncc(Cn2cc(cn2)C#N)c1

InChI Key InChIKey=LTFUKJDAZVVHNM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492878   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM492878(N-((3-chloro-6-fluoro- 1H-indol-5-yl)methyl)- 5-((...)
Affinity DataIC50:  5.50E+3nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent