BDBM492879 5-((4-carbamoyl-1H- pyrazol-1-yl)methyl)-N- ((3-chloro-6-fluoro-1H- indol-5- yl)methyl)nicotinamide::US10981893, Example 8

SMILES NC(=O)c1cnn(Cc2cncc(c2)C(=O)NCc2cc3c(Cl)c[nH]c3cc2F)c1

InChI Key InChIKey=NCFVJBQEAZDLPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492879   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM492879(5-((4-carbamoyl-1H- pyrazol-1-yl)methyl)-N- ((3-ch...)
Affinity DataIC50:  1.00E+4nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent