BDBM492880 N-((3-chloro-6-fluoro- 1H-indol-5-yl)methyl)- 2-((3-((N- cyclopropylacetamido) methyl)-1H-pyrazol-1- yl)methyl) isonicotinamide::US10981893, Example 9

SMILES CC(=O)N(Cc1ccn(Cc2cc(ccn2)C(=O)NCc2cc3c(Cl)c[nH]c3cc2F)n1)C1CC1

InChI Key InChIKey=ZTVDWIQBZNDENP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492880   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM492880(N-((3-chloro-6-fluoro- 1H-indol-5-yl)methyl)- 2-((...)
Affinity DataIC50:  1.00E+4nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent