BDBM492882 N-(2-amino-1-(5- chloro-1H-indazol-3- yl)-2-oxoethyl)-5-(4- ((2-oxopyridin-1(2H)- yl)methyl)benzyl) nicotinamide::US10981893, Example 11

SMILES NC(=O)C(NC(=O)c1cncc(Cc2ccc(Cn3ccccc3=O)cc2)c1)c1n[nH]c2ccc(Cl)cc12

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492882   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM492882(N-(2-amino-1-(5- chloro-1H-indazol-3- yl)-2-oxoeth...)
Affinity DataIC50:  5.50E+3nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent