BDBM492888 N-((3-chloro-6-fluoro- 1H-indol-5-yl)methyl)- 6-oxo-1-((3-((2- oxopyridin-1(2H)- yl)methyl)bicyclo[1.1.1] pentan-1-yl)methyl)- 1,6-dihydropyridine-3- carboxamide::US10981893, Example 17

SMILES Fc1cc2[nH]cc(Cl)c2cc1CNC(=O)c1ccc(=O)n(CC23CC(Cn4ccccc4=O)(C2)C3)c1

InChI Key InChIKey=VWUFVUIAMMZKSK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492888   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM492888(N-((3-chloro-6-fluoro- 1H-indol-5-yl)methyl)- 6-ox...)
Affinity DataIC50:  5.50E+3nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent