BDBM492891 N-((3- aminobenzo[d]isoxazol- 6-yl)methyl)-2-(3- (methylsulfonyl)-4-((2- oxopyridin-1(2H)- yl)methyl)benzyl) isonicotinamide::US10981893, Example 20

SMILES Cc1cc(Cc2cc(ccn2)C(=O)NCc2ccc3c(N)noc3c2)ccc1Cn1ccccc1=O

InChI Key InChIKey=HSHFXCSEZIQOJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492891   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM492891(N-((3- aminobenzo[d]isoxazol- 6-yl)methyl)-2-(3- (...)
Affinity DataIC50:  550nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent