BDBM492897 N-((6-amino-2- (trifluoromethyl)pyridin- 3-yl)methyl)-2-(3- (methylsulfonyl)-4-((2- oxopyridin-1(2H)- yl)methyl)benzyl) isonicotinamide::US10981893, Example 26

SMILES CS(=O)(=O)c1cc(Cc2cc(ccn2)C(=O)NCc2ccc(N)nc2C(F)(F)F)ccc1Cn1ccccc1=O

InChI Key InChIKey=IKDANPKBIBXTJU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492897   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM492897(N-((6-amino-2- (trifluoromethyl)pyridin- 3-yl)meth...)
Affinity DataIC50:  5.50E+3nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent