BDBM492900 N-((3-chloro-1H-indol- 5-yl)methyl)-2-(3- (methylsulfonyl)-4-((2- oxopyridin-1(2H)- yl)methyl)benzyl) isonicotinamide::US10981893, Example 29
SMILES CS(=O)(=O)c1cc(Cc2cc(ccn2)C(=O)NCc2cnc3[nH]cc(Cl)c3c2)ccc1Cn1ccccc1=O
InChI Key InChIKey=HQQGTGOLZSFJSE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 492900
Affinity DataIC50: <100nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Inhibition of human plasma kallikrein usingPro-Phe-Arg-AMC as substrate incubated for 5 minsMore data for this Ligand-Target Pair
Affinity DataEC50: <100nMAssay Description:All dilutions were prepared in an assay buffer comprising 50 mM Tris-HCl pH 7.2, 150 mM NaCl, and 0.01% Triton X-100.Four fold serial dilutions were ...More data for this Ligand-Target Pair