BDBM492901 N-((5-chloro-1H- indazol-3-yl)methyl)-2- (3-(methylsulfonyl)-4- ((2-oxopyridin-1(2H)- yl)methyl)benzyl) isonicotinamide::US10981893, Example 30

SMILES CS(=O)(=O)c1cc(Cc2cc(ccn2)C(=O)NCc2n[nH]c3ccc(Cl)cc23)ccc1Cn1ccccc1=O

InChI Key InChIKey=BXJIPBXGIFVHTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492901   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM492901(N-((5-chloro-1H- indazol-3-yl)methyl)-2- (3-(methy...)
Affinity DataIC50: <100nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent