BDBM493583 US10988445, Example 101
SMILES CCS(=O)(=O)c1ccc2C(N(Cc2c1)C=O)C(=O)Nc1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F
InChI Key InChIKey=FYIJFWZBSFEMNI-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 493583
Affinity DataIC50: 50.1nMAssay Description:The scintillation proximity assay (SPA) was run in white polystyrene flat-bottom 384-well plates (Greiner, cat. No. 781075). Assays were carried out ...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 121nMAssay Description:Inverse agonist activity at human RORC2 assessed as inhibition of SRC1-derived coactivator peptide by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 31.6nMAssay Description:The assay was run in black 384 well plates (Greiner cat no: 784900). Various concentrations of test ligands in 0.1 microlitres DMSO were dispensed to...More data for this Ligand-Target Pair