BDBM493604 US10988445, Example 200

SMILES OC(c1ccc(NC(=O)C2NCc3cc(ccc23)S(=O)(=O)CC2CC2)cc1)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=SUVGZKSEQPLCRW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 493604   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM493604(US10988445, Example 200)
Affinity DataIC50:  15.8nMAssay Description:The assay was run in black 384 well plates (Greiner cat no: 784900). Various concentrations of test ligands in 0.1 microlitres DMSO were dispensed to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM493604(US10988445, Example 200)
Affinity DataIC50:  63.1nMAssay Description:The scintillation proximity assay (SPA) was run in white polystyrene flat-bottom 384-well plates (Greiner, cat. No. 781075). Assays were carried out ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent