BDBM493616 US10988445, Example 211

SMILES NC(C1CC1)C(=O)N1Cc2cc(ccc2C1C(=O)Nc1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)CC1CC1

InChI Key InChIKey=INSJUDUKIJJBPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 493616   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM493616(US10988445, Example 211)
Affinity DataIC50:  50.1nMAssay Description:The assay was run in black 384 well plates (Greiner cat no: 784900). Various concentrations of test ligands in 0.1 microlitres DMSO were dispensed to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM493616(US10988445, Example 211)
Affinity DataIC50:  200nMAssay Description:The scintillation proximity assay (SPA) was run in white polystyrene flat-bottom 384-well plates (Greiner, cat. No. 781075). Assays were carried out ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent