BDBM493984 US10988478, Example 346::US10988478, Example 347::US10988478, Example 45

SMILES C[C@@]1(CO)Cc2cc(NC(=O)c3cnn4cccnc34)c(cc2O1)N1CCC(F)(CO)CC1

InChI Key InChIKey=XQCGRWQJQSYMGC-QFIPXVFZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 493984   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM493984(US10988478, Example 346 | US10988478, Example 347 ...)
Affinity DataKi:  1.90nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM493984(US10988478, Example 346 | US10988478, Example 347 ...)
Affinity DataKi:  2.90nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM493984(US10988478, Example 346 | US10988478, Example 347 ...)
Affinity DataKi:  3.60nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent