BDBM494139 US10988481, Compound 14

SMILES Oc1ccc2C[C@H]3N(CC[C@@]45C(Oc1c24)[C@@H](CC[C@@]35O)NC(=O)c1ccc2cc[nH]c2c1)C1CC1

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 494139   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494139(US10988481, Compound 14)
Affinity DataKi:  0.166nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494139(US10988481, Compound 14)
Affinity DataKi:  0.25nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494139(US10988481, Compound 14)
Affinity DataKi:  6.23nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent