BDBM495086 US10995072, Example 53

SMILES Fc1ccc(C(=O)c2ncc[nH]2)c2c3ccccc3oc12

InChI Key InChIKey=AUUFAYIMLKJTIL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 495086   

TargetProteinase-activated receptor 2(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM495086(US10995072, Example 53)
Affinity DataIC50:  5.42E+3nMAssay Description:Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 2(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM495086(US10995072, Example 53)
Affinity DataIC50:  1.63E+3nMAssay Description:Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent