BDBM495109 US10995084, Ex. No. 4B-15
SMILES COc1cc(ccc1Oc1cc(C)n[nH]c1=O)C(=O)N[C@H](C)C(=O)N1[C@@H](CC[C@@H]1C(C)(C)C#N)c1cccc(Cl)c1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 495109
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Kissei Pharmaceutical
US Patent
Kissei Pharmaceutical
US Patent
Affinity DataKi: 0.0900nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Kissei Pharmaceutical
US Patent
Kissei Pharmaceutical
US Patent
Affinity DataIC50: 0.170nMAssay Description:The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...More data for this Ligand-Target Pair