BDBM499854 (4-(((3R,6S)-6-((S)-1- aminoethyl)tetrahydro-2H-pyran-3- yl)amino)-7H-pyrrolo[2,3-d]pyrimidin- 5-yl)(2-chloro-4- phenoxyphenyl)methanone::US11020398, Compound I-166

SMILES C[C@H](N)[C@@H]1CC[C@H](CO1)Nc1ncnc2[nH]cc(C(=O)c3ccc(Oc4ccccc4)cc3Cl)c12

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 499854   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Arqule

US Patent
LigandPNGBDBM499854((4-(((3R,6S)-6-((S)-1- aminoethyl)tetrahydro-2H-py...)
Affinity DataIC50:  1.10nMAssay Description:Full length unphosphorylated form of BTK expressed in Sf9 cells was employed to test inhibitory activity in the inactive BTK assay. The assay was mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent