BDBM50000841 5-[3-Fluoro-5-(4-methoxy-tetrahydro-pyran-4-yl)-phenoxymethyl]-1,3-dimethyl-1,3-dihydro-benzoimidazol-2-one::CHEMBL315632

SMILES COC1(CCOCC1)c1cc(F)cc(OCc2ccc3n(C)c(=O)n(C)c3c2)c1

InChI Key InChIKey=IDPBUVZSNZBYNP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000841   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000841(5-[3-Fluoro-5-(4-methoxy-tetrahydro-pyran-4-yl)-ph...)
Affinity DataIC50:  80nMAssay Description:In vitro inhibition of leukotriene B4 synthesis in human whole blood by inhibiting 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed