BDBM50001264 5,7-Dichloro-4-hydroxy-3-p-tolyl-1H-quinolin-2-one::CHEMBL419940

SMILES Cc1ccc(cc1)-c1c(O)c2c(Cl)cc(Cl)cc2[nH]c1=O

InChI Key InChIKey=DZTJUPACBLYKGU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50001264   

TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001264(5,7-Dichloro-4-hydroxy-3-p-tolyl-1H-quinolin-2-one...)
Affinity DataKi:  300nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001264(5,7-Dichloro-4-hydroxy-3-p-tolyl-1H-quinolin-2-one...)
Affinity DataIC50:  550nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed