BDBM50001486 (betaCCE)9H-beta-Carboline-3-carboxylic acid ethyl ester::9H-beta-Carboline-3-carboxylic acid ethyl ester::9H-beta-Carboline-3-carboxylic acid ethyl ester (BCCE)::9H-beta-Carboline-3-carboxylic acid ethyl ester(BCCE)::9H-beta-Carboline-3-carboxylic acid ethyl ester(beta-CCE)::CHEMBL11709

SMILES CCOC(=O)c1cc2c(c[nH]1)nc1ccccc21

InChI Key InChIKey=QWWODAPIEHJFQG-UHFFFAOYSA-N

Data  10 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50001486   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50001486((betaCCE)9H-beta-Carboline-3-carboxylic acid ethyl...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-1-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50001486((betaCCE)9H-beta-Carboline-3-carboxylic acid ethyl...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity measured using LtK- cell membranes expressing GABA alpha1-beta3-gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50001486((betaCCE)9H-beta-Carboline-3-carboxylic acid ethyl...)
Affinity DataKi:  4.90nMAssay Description:Binding affinity to human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-2-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50001486((betaCCE)9H-beta-Carboline-3-carboxylic acid ethyl...)
Affinity DataKi:  4.90nMAssay Description:Binding affinity measured using LtK- cell membranes expressing GABA alpha2-beta3-gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50001486((betaCCE)9H-beta-Carboline-3-carboxylic acid ethyl...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-3-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50001486((betaCCE)9H-beta-Carboline-3-carboxylic acid ethyl...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity measured using LtK- cell membranes expressing GABA alpha3-beta3-gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50001486((betaCCE)9H-beta-Carboline-3-carboxylic acid ethyl...)
Affinity DataKi:  26.8nMAssay Description:Binding affinity measured using LtK- cell membranes expressing Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50001486((betaCCE)9H-beta-Carboline-3-carboxylic acid ethyl...)
Affinity DataKi:  27nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-5-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50001486((betaCCE)9H-beta-Carboline-3-carboxylic acid ethyl...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity measured using LtK- cell membranes expressing Gamma-aminobutyric-acid A receptor alpha6-beta3-gamma2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50001486((betaCCE)9H-beta-Carboline-3-carboxylic acid ethyl...)
Affinity DataKi:  2.70E+3nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-6-beta-3-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50001486((betaCCE)9H-beta-Carboline-3-carboxylic acid ethyl...)
Affinity DataIC50:  800nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed