BDBM50001782 (Lu 26-042)1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL331545

SMILES CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3cc(Cl)ccc23)C1=O

InChI Key InChIKey=NIMNILHFXBBMBV-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50001782   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001782((Lu 26-042)1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1...)
Affinity DataIC50:  130nMAssay Description:Compound was tested for the displacement of [3H]-spiperone from Dopamine receptor D2 from rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001782((Lu 26-042)1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1...)
Affinity DataIC50:  130nMAssay Description:Displacement of [3H]-spiperone from Dopamine receptor D2 rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001782((Lu 26-042)1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1...)
Affinity DataIC50:  70nMAssay Description:Displacement of [3H]-prazosin from Alpha-1 adrenergic receptor in whole rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001782((Lu 26-042)1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1...)
Affinity DataIC50:  130nMAssay Description:Binding affinity to dopamine receptor D2 using a [3H]-spiperone binding assay in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001782((Lu 26-042)1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1...)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001782((Lu 26-042)1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity to serotonin 5-hydroxytryptamine 2A receptors using a radioligand [3H]-ketanserin binding assay in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001782((Lu 26-042)1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1...)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001782((Lu 26-042)1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1...)
Affinity DataIC50:  70nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001782((Lu 26-042)1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1...)
Affinity DataIC50:  70nMAssay Description:Binding affinity to the alpha-1 adrenergic receptor using a radioligand [3H]-prazosin binding assay in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed