BDBM50001796 1-(2-{4-[1-(4-Fluoro-phenyl)-6-methyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL144086

SMILES Cc1ccc2c(cn(-c3ccc(F)cc3)c2c1)C1CCN(CCN2CCNC2=O)CC1

InChI Key InChIKey=HTLQTFJVKLZPQC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001796   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001796(1-(2-{4-[1-(4-Fluoro-phenyl)-6-methyl-1H-indol-3-y...)
Affinity DataIC50:  270nMAssay Description:Displacement of [3H]-spiperone from Dopamine receptor D2 from rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001796(1-(2-{4-[1-(4-Fluoro-phenyl)-6-methyl-1H-indol-3-y...)
Affinity DataIC50:  0.820nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001796(1-(2-{4-[1-(4-Fluoro-phenyl)-6-methyl-1H-indol-3-y...)
Affinity DataIC50:  24nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed