BDBM50003057 7-Amino-1,2,3-trimethyl-2,8-dihydro-2,5,6,8-tetraaza-cyclopenta[a]naphthalen-9-one::CHEMBL122959
SMILES Cc1n(C)c(C)c2c1cnc1nc(N)[nH]c(=O)c21
InChI Key InChIKey=WNAFKDMXNUMRHW-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50003057
Affinity DataIC50: >9.50E+4nMAssay Description:Compound was evaluated for the inhibition of recombinant human Dihydrofolate reductase (DHFR); no inhibitionMore data for this Ligand-Target Pair
Affinity DataIC50: 9.50E+4nMAssay Description:Compound was evaluated for the inhibition of Lactobacillus casei thymidylate synthaseMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >9.50E+4nMAssay Description:Compound was evaluated for the inhibition of Aminoimidazole carboxamide ribonucleotide formyl transferase (AICAR) with (6R) tetrahydrofolate as subst...More data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >9.50E+4nMAssay Description:Compound was evaluated for the inhibition of Glycinamide ribonucleotide formyl transferase (GAR) with formyl (6R) tetrahydrofolate as substrateMore data for this Ligand-Target Pair